Diabetes Metab J 2018;42:355-363. Hwang YC, Jun JE, Jeong IK, Ahn KJ, Chung HY. Lipids Health Dis. Demystifying the management of hypertriglyceridaemia. Naito R, Miyauchi K, Daida H. Racial differences in the cholesterol-lowering effect of statin. 3. Kim BY, Won JC, Lee JH, Kim HS, Park JH, Ha KH, Won KC, Kim DJ, Park KS. Pharmacologic options for aggressive low-density lipoprotein cholesterol lowering: benefits versus risks. The objective of this study was designed TaskForce Team for the Diabetes Fact Sheet of the Korean Diabetes Association. 4. eCollection 2020. 11. Clin Ther. Response: efficacy of moderate intensity statins in the treatment of dyslipidemia in Korean patients with type 2 diabetes mellitus (Diabetes Metab J 2017;41: 23-30). Effects of rosuvastatin versus atorvastatin, simvastatin, and pravastatin on non-high-density lipoprotein cholesterol, apolipoproteins, and lipid ratios in patients with hypercholesterolemia: additional results from the STELLAR trial. In this multicenter, parallel-group, open-label trial, adults with hypercholesterolemia were randomized to treatments with rosuvastatin 10, 20, 40, or 80 mg, atorvastatin 10, 20, 40, or 80 mg, simvastatin 10, 20, 40, or 80 mg, or pravastatin 10, 20, or 40 mg. Efficacy and safety results from this trial have been previously published. Epub 2018 Jan 15. Kim KJ, Kwon TY, Yu S, Seo JA, Kim NH, Choi KM, Baik SH, Choi DS, Kim SG, Park Y, Kim NH. Comparison of low-density lipoprotein cholesterol reduction after switching patients on other statins to rosuvastatin or simvastatin in a real-world clinical practice setting. HHS 2020 Jan 4;19(1):1. doi: 10.1186/s12944-019-1182-5. 2019. Diabetes Metab J 2018;42:394-401. All rights reserved. Messenger RNA levels of genes involved in dysregulation of postprandial lipoproteins in type 2 diabetes: the role of Niemann-Pick C1-like 1, ATP-binding cassette, transporters G5 and G8, and of microsomal triglyceride transfer protein. Diabetes Metab J 2019;43:582-589. 1. Clin Ther. Kim MK, Ko SH, Kim BY, Kang ES, Noh J, Kim SK, Park SO, Hur KY, Chon S, Moon MK, Kim NH, Kim SY, Rhee SY, Lee KW, Kim JH, Rhee EJ, Chun S, Yu SH, Kim DJ, Kwon HS, Park KS. rosuvastatin 20 mg showed good efficacy and safety profile.10,11 Therefore, a combination of ARB and CCB with rosuvastatin was ex-pected to show excellent efficacy and safety in patients with hyper-tension and dyslipidemia. Get the latest research from NIH: https://www.nih.gov/coronavirus. Letter: Comparison of the Efficacy of Rosuvastatin Monotherapy 20 mg with Rosuvastatin 5 mg and Ezetimibe 10 mg Combination Therapy on Lipid Parameters in Patients with Type 2 Diabetes Mellitus (, Copyrighted Material Permission or Copyright Permission, http://creativecommons.org/licenses/by-nc/4.0/. Past and current status of adult type 2 diabetes mellitus management in Korea: a national health insurance service database analysis. This site needs JavaScript to work properly. As mentioned by the authors, a long-term follow-up study with a larger sample and cardiovascular outcome are needed to assess the clinical significance of this study. Dechkhajorn W, Maneerat Y, Prasongsukarn K, Kanchanaphum P, Kumsiri R. Scientifica (Cairo). Strandberg TE, Feely J, Sigurdsson EL; DISCOVERY study group. Copyright © 2019 Korean Diabetes Association. Diabetes Metab J 2019;43:398-406. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. doi: 10.1016/j.amjcard.2005.06.007. Nat Rev Cardiol 2013;10:648-661. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. Watts GF, Ooi EM, Chan DC. Therefore, our aim in this study was to compare the efficacy of daily 20 mg rosuvastatin monotherapy with that of daily 5 mg rosuvastatin/10 mg ezetimibe combination therapy daily on lipid parameters, including apoB/A1 ratio, in patients with type 2 diabetes mellitus (T2DM). CONFLICTS OF INTEREST: No potential conflict of interest relevant to this article was reported. Please enable it to take advantage of the complete set of features! Lally S, Tan CY, Owens D, Tomkin GH. 8. The additional analyses included in this report show that 53% (83/156) to 80% (125/157) of patients in the rosuvastatin 10- to 40-mg groups achieved LDL-C levels < 100 mg/dl (< 2.6 mmol/l), compared with 18% (28/158) to 70% (115/165) of patients who received atorvastatin, 8% (13/165) to 53% (86/163) of patients who received simvastatin, and 1% (1/160) to 8% (13/161) of patients who received pravastatin. Interleukin-8 in Hyperlipidemia and Coronary Heart Disease in Thai Patients Taking Statin Cholesterol-Lowering Medication While Undergoing Coronary Artery Bypass Grafting Treatment. Diabetes Metab J 2017;41:152-153. Current and emerging treatments for hypercholesterolemia: A focus on statins and proprotein convertase subtilisin/kexin Type 9 inhibitors for perioperative clinicians. In the article entitled ‘Comparison of the efficacy of rosuvastatin monotherapy 20 mg with rosuvastatin 5 mg and ezetimibe 10 mg combination therapy on lipid parameters in patients with type 2 diabetes mellitus,’ Hwang et al. 9. Ko SH, Han K, Lee YH, Noh J, Park CY, Kim DJ, Jung CH, Lee KU, Ko KS.  |  Twelve-week, multicenter, randomized, open-label comparison of the effects of rosuvastatin 10 mg/d and atorvastatin 10 mg/d in high-risk adults: a DISCOVERY study. The prevalence of diabetes among Korean adults aged 30 years and older was 13.7% (4.8 million) in 2013 to 2014 and 14.4% (5.02 million) in 2016 [, In the article entitled ‘Comparison of the efficacy of rosuvastatin monotherapy 20 mg with rosuvastatin 5 mg and ezetimibe 10 mg combination therapy on lipid parameters in patients with type 2 diabetes mellitus,’ Hwang et al. This study compared the efficacy and safety of low doses of rosuvastatin (10 mg) and atorvastatin (20 mg) in high-risk patients with hypercholesterolemia. The efficacy of statin in Asian populations differs from that in Caucasians. In this multicenter, parallel-group, open-label trial, adults with hypercholesterolemia were randomized to treatments with rosuvastatin 10, 20, 40, or 80 mg, atorvastatin 10, 20, 40, or 80 mg, simvastatin 10, 20, 40, or 80 mg, or pravastatin 10, 20, or 40 mg. Efficacy and safety results from this trial have been previously published. Diabetes fact sheets in Korea, 2018: an appraisal of current status. Comparison of the efficacy of rosuvastatin monotherapy 20 mg with rosuvastatin 5 mg and ezetimibe 10 mg combination therapy on lipid parameters in patients with type 2 diabetes mellitus. Many patients at high risk of cardiovascular disease do not achieve recommended low-density lipoprotein cholesterol (LDL-C) goals. Patients mostly received rosuvastatin 20 mg, rosuvastatin 40 mg, or atorvastatin 40 mg. See footnote to Table VI for details of numbers of patients receiving each dose. Am J Cardiol. In this study, all variables were well-matched, and there were no initial differences between the two groups, including baseline lipid parameters except triglycerides (135.5±47.7 mg/dL in rosuvastatin 20 mg/day group vs. 173.1±64.1 mg/dL in rosuvastatin/ezetimibe 5/10 mg group, Korean diabetes association recommended LDL-C be <100 mg/dL in diabetic patients without CVD [. Committee of Clinical Practice Guidelines, Korean Diabetes Association. 2005 Aug 22;96(4A):60E-66E. A statin dose that is lower than that used in Caucasian populations can be used to achieve a similar therapeutic effect in Asian populations [. 2004 Nov;26(11):1821-33. doi: 10.1016/j.clinthera.2004.11.015. Kwak A, Kim JH, Choi CU, Kim IW, Oh JM, Kim K. Int J Clin Pharm. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. 2004 Sep;26(9):1388-99. doi: 10.1016/j.clinthera.2004.09.006. Comparison of the efficacy of rosuvastatin monotherapy 20 mg with rosuvastatin 5 mg and ezetimibe 10 mg combination therapy on lipid parameters in patients with type 2 diabetes mellitus. Lee CH, Lee SW, Park SW. Diabetes and subclinical coronary atherosclerosis. Copyright © 2020 by Korean Diabetes Association. Get the latest public health information from CDC: https://www.coronavirus.gov. 2. Diabetes fact sheet in Korea, 2016: an appraisal of current status. Other additional analyses showed that more patients in the rosuvastatin 10- to 40-mg groups than in the comparator groups who were at high risk of coronary heart disease according to National Cholesterol Education Program Adult Treatment Panel (ATP) III, Joint European Societies, or Canadian guidelines achieved the LDL-C goals of < 100 mg/dl (< 2.6 mmol/l) (55% to 77% compared with 0 to 64%), < 3.0 mmol/l (< 116 mg/dl) (76% to 94% compared with 6% to 81%), and < 2.5 mmol/l (< 97 mg/dl) (47% to 69% compared with 0 to 53%), respectively. Comparison of rosuvastatin with atorvastatin, simvastatin and pravastatin in achieving cholesterol goals and improving plasma lipids in hypercholesterolaemic patients with or without the metabolic syndrome in the MERCURY I trial. Jones PH, Hunninghake DB, Ferdinand KC, Stein EA, Gold A, Caplan RJ, Blasetto JW; Statin Therapies for Elevated Lipid Levels Compared Across Doses to Rosuvastatin Study Group. 2019 Apr;41(2):460-469. doi: 10.1007/s11096-019-00810-w. Epub 2019 Mar 12. Clujul Med. Results favoring rosuvastatin versus the comparators were also reported for patients: (a) who had triglycerides > or = 200mg/dl (> or = 2.3 mmol/l), and achieved both ATP III LDL-C and non-high-density lipoprotein cholesterol (non-HDL-C) goals (80% to 84% versus 15% to 84%); (b) overall who achieved the Canadian LDL-C goals of < 2.5 (< 97 mg/dl) to < 5.0 mmol/l (< 193 mg/dl) (85% to 91% versus 44% to 86%); and (c) who achieved all 3 Canadian goals for LDL-C, triglycerides (< 3.0 mmol/l [< 266 mg/dl] to < 2.0 mmol/l [< 177 mg/dl]), and the total cholesterol/high-density lipoproteincholesterol ratio (< 4 to < 7) (70% to 83% versus 35% to 79%). Diabetologia 2006;49:1008-1016. Fox KM, Gandhi SK, Ohsfeldt RL, Davidson MH. 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Interleukin-8 in Hyperlipidemia and Coronary Heart disease in Thai patients Taking statin Cholesterol-Lowering Medication Undergoing., won KC, Kim JH, Kang ES, won KC, Kim IW, JM! Focus on statins and proprotein convertase subtilisin/kexin type 9 inhibitors for perioperative.... Lipids: sources of variation among results from published studies and composite predicted.... 2004 Sep ; 26 ( 9 ):1388-99. doi: 10.1007/s11096-019-00810-w. Epub 2019 Mar 12 fact sheet in,! Of Internal Medicine, the Catholic University of Korea, 2018: an appraisal of current status statin in... And statins versus a double dose of statin monotherapy in participants with hypercholesterolemia: a meta-analysis of literature peritoneal...

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